Reaction Details Report a problem with these data
Target
Adenosine receptor A2a
Ligand
BDBM50451378
Substrate
n/a
Meas. Tech.
ChEMBL_30285 (CHEMBL642080)
EC50
0.000±n/a nM
Comments
From 0 on 20220115
Citation
 Chordia, MD; Murphree, LJ; Macdonald, TL; Linden, J; Olsson, RA 2-Aminothiazoles: a new class of agonist allosteric enhancers of A(1) adenosine receptors. Bioorg Med Chem Lett 12:1563-6 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50451378
Synonyms:
CHEMBL39106
Type:
Small organic molecule
Emp. Form.:
C13H13IN2O2S
Mol. Mass.:
388.224
SMILES:
I.CC(=O)Oc1ccc2-c3nc(N)sc3CCc2c1
Structure:
Search PDB for entries with ligand similarity: