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Reaction Details
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TargetMelatonin receptor
LigandBDBM50114718
Substrate/Competitorn/a
Meas. Tech.ChEMBL_105099
Ki 0.01±n/a nM
Citation Wallez, VDurieux-Poissonnier, SChavatte, PBoutin, JAAudinot, VNicolas, JPBennejean, CDelagrange, PRenard, PLesieur, D Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands. J Med Chem45:2788-800 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Melatonin receptor
Name:Melatonin receptor
Synonyms:MTNR1A | MTNR1A protein | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:Enzyme
Mol. Mass.:39392.94
Organism:Homo sapiens (Human)
Description:P48039
Residue:350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50114718
NameBDBM50114718
Synonyms:But-3-enoic acid [2-(5-methoxy-2-phenyl-benzofuran-3-yl)-ethyl]-amide | CHEMBL330137
TypeSmall organic molecule
Emp. Form.C21H21NO3
Mol. Mass.335.3963
SMILESCOc1ccc2oc(c(CCNC(=O)CC=C)c2c1)-c1ccccc1
Structure
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