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Target
Translocator protein
Ligand
BDBM50118542
Substrate
n/a
Meas. Tech.
ChEMBL_37198 (CHEMBL650799)
Ki
0.56±n/a nM
Citation
 Campiani, G; Ramunno, A; Fiorini, I; Nacci, V; Morelli, E; Novellino, E; Goegan, M; Mennini, T; Sullivan, S; Zisterer, DM; Williams, CD Synthesis of new molecular probes for investigation of steroid biosynthesis induced by selective interaction with peripheral type benzodiazepine receptors (PBR). J Med Chem 45:4276-81 (2002) [PubMed]  Article 
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE
  
Inhibitor
Name:
BDBM50118542
Synonyms:
CHEMBL335300 | Diethyl-carbamic acid 5-m-tolyl-6-oxa-10,10b-diaza-benzo[e]azulen-4-yl ester
Type:
Small organic molecule
Emp. Form.:
C23H23N3O3
Mol. Mass.:
389.447
SMILES:
CCN(CC)C(=O)OC1=C(Oc2cccnc2-n2cccc12)c1cccc(C)c1 |t:8|
Structure:
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