Target
5-hydroxytryptamine receptor 3A
Ligand
BDBM50094968
Substrate
n/a
Meas. Tech.
ChEMBL_3474 (CHEMBL618890)
Ki
>10000±n/a nM
Citation
 Ferretti, GDukat, MGiannella, MPiergentili, APigini, MQuaglia, WDamaj, MIMartin, BRGlennon, RA Homoazanicotine: a structure-affinity study for nicotinic acetylcholine (nACh) receptor binding. J Med Chem 45:4724-31 (2002) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 3A
Synonyms:
5-HT-3 | 5-HT3 | 5-HT3A | 5-HT3R | 5-hydroxytryptamine receptor 3 (5-HT3) | 5-hydroxytryptamine receptor 3A (5-HT3a) | 5-hydroxytryptamine receptor 3A (5HT3A) | 5HT3A_HUMAN | 5HT3R | HTR3 | HTR3A | Serotonin 3 (5-HT3) receptor | Serotonin 3 receptor (5HT3) | Serotonin receptor 3A | Serotonin-gated ion channel receptor | Serotonin-gated ion channel receptor 3
Type:
Protein
Mol. Mass.:
55283.27
Organism:
Homo sapiens (Human)
Description:
P46098
Residue:
478
Sequence:
MLLWVQQALLALLLPTLLAQGEARRSRNTTRPALLRLSDYLLTNYRKGVRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDFDNITKLSIPTDSIWVPDILINEFVDVGKSPNIPYVYIRHQGEVQNYKPLQVVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFREFSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQDLQQPVPAWLRHLVLERIAWLLCLREQSTSQRPPATSQATKTDDCSAMGNHCSHMGGPQDFEKSPRDRCSPPPPPREASLAVCGLLQELSSIRQFLEKRDEIREVARDWLRVGSVLDKLLFHIYLLAVLAYSITLVMLWSIWQYA
  
Inhibitor
Name:
BDBM50094968
Synonyms:
3-(1-Methyl-4,5-dihydro-1H-imidazol-2-ylmethyl)-pyridine | CHEMBL313631
Type:
Small organic molecule
Emp. Form.:
C10H13N3
Mol. Mass.:
175.2303
SMILES:
CN1CCN=C1Cc1cccnc1 |c:4|
Structure:
Search PDB for entries with ligand similarity: