Reaction Details Report a problem with these data
Target
Fibroblast growth factor 2
Ligand
BDBM50000130
Substrate
n/a
Meas. Tech.
ChEMBL_70467 (CHEMBL676958)
IC50
25.2±n/a nM
Citation
Murphy, PV; Pitt, N; O'Brien, A; Enright, PM; Dunne, A; Wilson, SJ; Duane, RM; O'Boyle, KM Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library. Bioorg Med Chem Lett 12:3287-90 (2002) [PubMed] Article
More Info.:
Target
Name:
Fibroblast growth factor 2
Synonyms:
Basic fibroblast growth factor | FGF-2 | FGF2 | FGF2_HUMAN | FGFB | Fibroblast growth factor 2 (bFGF) | Fibroblast growth factor receptor 2 (FGF-2) | HBGF-2 | Heparin-binding growth factor 2
Type:
Protein
Mol. Mass.:
30803.89
Organism:
Homo sapiens (Human)
Description:
P09038
Residue:
288
Sequence:
MVGVGGGDVEDVTPRPGGCQISGRGARGCNGIPGAAAWEAALPRRRPRRHPSVNPRSRAAGSPRTRGRRTEERPSGSRLGDRGRGRALPGGRLGGRGRGRAPERVGGRGRGRGTAAPRAAPAARGSRPGPAGTMAAGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS