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TargetOpioid receptors; mu & delta
LigandBDBM50121640
Substrate/Competitorn/a
Meas. Tech.ChEMBL_146915
Ki 0.12±n/a nM
Citation Bryant, SDGeorge, CFlippen-Anderson, JLDeschamps, JRSalvadori, SBalboni, GGuerrini, RLazarus, LH Crystal structures of dipeptides containing the Dmt-Tic pharmacophore. J Med Chem45:5506-13 (2002) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Opioid receptors; mu & delta
Name:Opioid receptors; mu & delta
Synonyms:Cytochrome P450 3A4 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor | Delta-type opioid receptor (DOR) | OPIATE Delta | Opiate Delta 1 | Opioid receptor | Opioid receptor A | Voltage-gated potassium channel
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:40465.04
Organism:Rattus norvegicus (rat)
Description:Competition binding assays were using CHO-K1 cell membranes expressing the opioid receptor.
Residue:372
Sequence:
MEPVPSARAELQFSLLANVSDTFPSAFPSASANASGSPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKLKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTQPRDGAVVCTLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDINRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRAPCGGQEPGSLRRPRQATARERVTAC
TPSDGPGGGAAA
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  Blast E-value cutoff:
BDBM50121640
NameBDBM50121640
Synonyms:2-[2-Dimethylamino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionyl]-1,2,3,4-tetrahydro-isoquinoline-4-carboxylic acid | CHEMBL150508
TypeSmall organic molecule
Emp. Form.C23H28N2O4
Mol. Mass.396.4794
SMILESCN(C)[C@@H](Cc1c(C)cc(O)cc1C)C(=O)N1CC(C(O)=O)c2ccccc2C1
Structure
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