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Target
5-hydroxytryptamine receptor 1A
Ligand
BDBM50122716
Substrate
n/a
Meas. Tech.
ChEMBL_1559 (CHEMBL616380)
IC50
9100.0±n/a nM
Citation
 Hinschberger, A; Butt, S; Lelong, V; Boulouard, M; Dumuis, A; Dauphin, F; Bureau, R; Pfeiffer, B; Renard, P; Rault, S New benzo[h][1,6]naphthyridine and azepino[3,2-c]quinoline derivatives as selective antagonists of 5-HT4 receptors: binding profile and pharmacological characterization. J Med Chem 46:138-47 (2002) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1A
Synonyms:
5-HT1A | 5-hydroxytryptamine receptor 1A | 5-hydroxytryptamine receptor 1A (5HT1A) | 5HT1A_MOUSE | Gpcr18 | Htr1a | Serotonin 1a (5-HT1a) receptor
Type:
Enzyme
Mol. Mass.:
46192.09
Organism:
Mus musculus (Mouse)
Description:
Q64264
Residue:
421
Sequence:
MDMFSLGQGNNTTTSLEPFGTGGNDTGLSNVTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLVLPMAALYQVLNKWTLGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALISLTWLIGFLISIPPMLGWRTPEDRSNPNECTISKDHGYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKKGAGTSFGTSSAPPPKKSLNGQPGSGDCRRSAENRAVGTPCANGAVRQGEDDATLEVIEVHRVGNSKGHLPLPSESGATSYVPACLERKNERTAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPFCESSCHMPELLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCR
  
Inhibitor
Name:
BDBM50122716
Synonyms:
5-(Piperidin-4-ylmethoxy)-9-propyl-1,2,3,4-tetrahydro-benzo[h][1,6]naphthyridine | CHEMBL35226
Type:
Small organic molecule
Emp. Form.:
C21H29N3O
Mol. Mass.:
339.4745
SMILES:
CCCN1CCC(COc2nc3ccccc3c3NCCCc23)CC1
Structure:
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