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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50126393
Substrate
n/a
Meas. Tech.
ChEMBL_106167 (CHEMBL718862)
IC50
25000±n/a nM
Citation
 Thompson, DA; Chai, BX; Rood, HL; Siani, MA; Douglas, NR; Gantz, I; Millhauser, GL Peptoid mimics of agouti related protein. Bioorg Med Chem Lett 13:1409-13 (2003) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50126393
Synonyms:
CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-ethyl)-carbamoyl]-methyl}-2-(3-guanidino-propylamino)-acetamide
Type:
Small organic molecule
Emp. Form.:
C31H39N7O3
Mol. Mass.:
557.6865
SMILES:
C[C@@H](N(CC(N)=O)C(=O)CN(C(c1ccccc1)c1ccccc1)C(=O)CNCCCNC(N)=N)c1ccccc1
Structure:
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