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Target
Synaptic vesicular amine transporter
Ligand
BDBM50129603
Substrate
n/a
Meas. Tech.
ChEMBL_213570 (CHEMBL816126)
Ki
207000±n/a nM
Citation
 Perera, RP; Wimalasena, DS; Wimalasena, K Characterization of a series of 3-amino-2-phenylpropene derivatives as novel bovine chromaffin vesicular monoamine transporter inhibitors. J Med Chem 46:2599-605 (2003) [PubMed]  Article 
Target
Name:
Synaptic vesicular amine transporter
Synonyms:
Monoamine transporter | SLC18A2 | Solute carrier family 18 member 2 | VAT2 | VMAT2 | VMAT2_BOVIN | Vesicular amine transporter 2
Type:
PROTEIN
Mol. Mass.:
55749.95
Organism:
Bos taurus
Description:
ChEMBL_469572
Residue:
517
Sequence:
MALSELALLRRLQESRHSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIEHEKDALEIQTAKPGLTASAPGSFQNIFSYYDNSTMVTGNSTDHLQGALVHEATTQHMATNSSSASSDCPSEDKDLLNENVQVGLLFASKATVQLLTNPFIGLLTNRIGYPIPMFTGFCIMFISTVMFAFSRTYAFLLIARSLQGIGSSCSSVAGMGMLASVYTDDEERGNAMGIALGGLAMGVLVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLRDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSHKWQLGVAFLPASVSYLIGTNVFGILAHKMGRWLCALLGMIIVGMSILCIPLAKNIYGLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPPAKEEKMAILMDHNCPIKTKMYTQNSSQSHPIGEDEESESD
  
Inhibitor
Name:
BDBM50129603
Synonyms:
4-(2-Diethylamino-1-methylene-propyl)-phenol | CHEMBL85122
Type:
Small organic molecule
Emp. Form.:
C14H21NO
Mol. Mass.:
219.3226
SMILES:
CCN(CC)C(C)C(=C)c1ccc(O)cc1
Structure:
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