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Target
High affinity immunoglobulin epsilon receptor subunit alpha
Ligand
BDBM50130413
Substrate
n/a
Meas. Tech.
ChEMBL_68796 (CHEMBL683435)
IC50
114000±n/a nM
Citation
 Buku, A; Mendlowitz, M; Condie, BA; Price, JA Histamine-releasing activity and binding to the FcepsilonRI alpha human mast cell receptor subunit of mast cell degranulating peptide analogues with alanine substitutions. J Med Chem 46:3008-12 (2003) [PubMed]  Article 
Target
Name:
High affinity immunoglobulin epsilon receptor subunit alpha
Synonyms:
FCE1A | FCER1A | FCERA_HUMAN | Fc-epsilon RI-alpha | FcERI | High affinity immunoglobulin epsilon receptor subunit alpha | IgE Fc receptor subunit alpha | IgE Fc receptor, alpha-subunit
Type:
PROTEIN
Mol. Mass.:
29595.99
Organism:
Homo sapiens (Human)
Description:
ChEMBL_68795
Residue:
257
Sequence:
MAPAMESPTLLCVALLFFAPDGVLAVPQKPKVSLNPPWNRIFKGENVTLTCNGNNFFEVSSTKWFHNGSLSEETNSSLNIVNAKFEDSGEYKCQHQQVNESEPVYLEVFSDWLLLQASAEVVMEGQPLFLRCHGWRNWDVYKVIYYKDGEALKYWYENHNISITNATVEDSGTYYCTGKVWQLDYESEPLNITVIKAPREKYWLQFFIPLLVVILFAVDTGLFISTQQQVTFLLKIKRTRKGFRLLNPHPKPNPKNN
  
Inhibitor
Name:
BDBM50130413
Synonyms:
CHEMBL411579 | IKCNCKRHVIKPHICRKICGKN-NH2
Type:
Small organic molecule
Emp. Form.:
C110H196N40O24S4
Mol. Mass.:
2591.247
SMILES:
CC[C@H](C)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(N)=O
Structure:
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