Reaction Details Report a problem with these data
Target
Peptide deformylase, mitochondrial
Ligand
BDBM50131291
Substrate
n/a
Meas. Tech.
ChEBML_154178
IC50
30±n/a nM
Citation
Davies, SJ; Ayscough, AP; Beckett, RP; Bragg, RA; Clements, JM; Doel, S; Grew, C; Launchbury, SB; Perkins, GM; Pratt, LM; Smith, HK; Spavold, ZM; Thomas, SW; Todd, RS; Whittaker, M Structure-activity relationships of the peptide deformylase inhibitor BB-3497: modification of the methylene spacer and the P1' side chain. Bioorg Med Chem Lett 13:2709-13 (2003) [PubMed] Article
More Info.:
Target
Name:
Peptide deformylase, mitochondrial
Synonyms:
DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:
PROTEIN
Mol. Mass.:
27023.25
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154318
Residue:
243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPPEPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMKVND