Reaction Details Report a problem with these data
Target
Peptide deformylase, mitochondrial
Ligand
BDBM50132672
Substrate
n/a
Meas. Tech.
ChEBML_154318
IC50
8390.0±n/a nM
Citation
 Takayama, W; Shirasaki, Y; Sakai, Y; Nakajima, E; Fujita, S; Sakamoto-Mizutani, K; Inoue, J Synthesis and PDF inhibitory activities of novel benzothiazolylidenehydroxamic acid derivatives. Bioorg Med Chem Lett 13:3273-6 (2003) [PubMed]  Article 
Target
Name:
Peptide deformylase, mitochondrial
Synonyms:
DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:
PROTEIN
Mol. Mass.:
27023.25
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154318
Residue:
243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPPEPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPRQVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLACVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMKVND
  
Inhibitor
Name:
BDBM50132672
Synonyms:
CHEMBL419929 | N-Hydroxy-2-[3-propyl-3H-benzothiazol-(2Z)-ylidene]-acetamide
Type:
Small organic molecule
Emp. Form.:
C12H14N2O2S
Mol. Mass.:
250.317
SMILES:
CCCN1\C(Sc2ccccc12)=C\C(=O)NO
Structure:
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