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Target
5-hydroxytryptamine receptor 7
Ligand
BDBM50139361
Substrate
n/a
Meas. Tech.
ChEBML_3690
Ki
4.1±n/a nM
Citation
 Thomson, CG; Beer, MS; Curtis, NR; Diggle, HJ; Handford, E; Kulagowski, JJ Thiazoles and thiopyridines: novel series of high affinity h5HT(7) ligands. Bioorg Med Chem Lett 14:677-80 (2004) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 7
Synonyms:
5-HT-7 | 5-HT-X | 5-HT7 | 5-HT7L | 5-HT7S | 5-HT7b | 5HT7 | 5HT7R_HUMAN | HTR7 | Serotonin receptor 7
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
53573.08
Organism:
Homo sapiens (Human)
Description:
P34969
Residue:
479
Sequence:
MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLSEVTASPAPTWDAPPDNASGCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDKVCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAAGMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD
  
Inhibitor
Name:
BDBM50139361
Synonyms:
2-(6-Bromopyridin-2-ylthio)-N,N-dimethylethanamine | CHEMBL158285 | [2-(6-Bromo-pyridin-2-ylsulfanyl)-ethyl]-dimethyl-amine
Type:
Small organic molecule
Emp. Form.:
C9H13BrN2S
Mol. Mass.:
261.182
SMILES:
CN(C)CCSc1cccc(Br)n1
Structure:
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