Reaction Details Report a problem with these data
Target
Phospholipase A2, major isoenzyme
Ligand
BDBM50139530
Substrate
n/a
Meas. Tech.
ChEBML_155880
Ki
15000±n/a nM
Citation
 Lin, G; Lin, YF; Hwang, MT; Lin, YZ Benzene-di-N-octylcarbamates as conformationally constrained phospholipase A(2) inhibitors. Bioorg Med Chem Lett 14:751-5 (2004) [PubMed]  Article 
Target
Name:
Phospholipase A2, major isoenzyme
Synonyms:
Group IB phospholipase A2 | PA21B_PIG | PLA2G1B | Phosphatidylcholine 2-acylhydrolase | Phospholipase A2
Type:
Hydrolase; monomer or homodimer
Mol. Mass.:
16279.83
Organism:
Sus scrofa (pig)
Description:
Purchased from Sigma.
Residue:
146
Sequence:
MKFLVLAVLLTVGAAQEGISSRALWQFRSMIKCAIPGSHPLMDFNNYGCYCGLGGSGTPVDELDRCCETHDNCYRDAKNLDSCKFLVDNPYTESYSYSCSNTEITCNSKNNACEAFICNCDRNAAICFSKAPYNKEHKNLDTKKYC
  
Inhibitor
Name:
BDBM50139530
Synonyms:
CHEMBL434865 | Octyl-carbamic acid 4-octylcarbamoyloxy-phenyl ester
Type:
Small organic molecule
Emp. Form.:
C24H40N2O4
Mol. Mass.:
420.5854
SMILES:
CCCCCCCCNC(=O)Oc1ccc(OC(=O)NCCCCCCCC)cc1
Structure:
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