Reaction Details Report a problem with these data
Target
Peptide deformylase
Ligand
BDBM50224041
Substrate
n/a
Meas. Tech.
ChEMBL_144950 (CHEMBL755896)
IC50
<5±n/a nM
Citation
Molteni, V; He, X; Nabakka, J; Yang, K; Kreusch, A; Gordon, P; Bursulaya, B; Warner, I; Shin, T; Biorac, T; Ryder, NS; Goldberg, R; Doughty, J; He, Y Identification of novel potent bicyclic peptide deformylase inhibitors. Bioorg Med Chem Lett 14:1477-81 (2004) [PubMed] Article
More Info.:
Target
Name:
Peptide deformylase
Synonyms:
DEF_STAAU | PDF | Peptide Deformylase | Polypeptide deformylase | def | def1 | pdf1
Type:
PROTEIN
Mol. Mass.:
20556.80
Organism:
Staphylococcus aureus (strain Mu50 / ATCC 700699)
Description:
ChEMBL_459563
Residue:
183
Sequence:
MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNSQDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQEAYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLNGVMFYDHIDKNHPLQPHTDAVEV