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Target
Dynamin-1
Ligand
BDBM50147556
Substrate
n/a
Meas. Tech.
ChEMBL_60877 (CHEMBL673524)
IC50
>300000±n/a nM
Citation
 Hill, TA; Odell, LR; Quan, A; Abagyan, R; Ferguson, G; Robinson, PJ; McCluskey, A Long chain amines and long chain ammonium salts as novel inhibitors of dynamin GTPase activity. Bioorg Med Chem Lett 14:3275-8 (2004) [PubMed]  Article 
Target
Name:
Dynamin-1
Synonyms:
DNM | DNM1 | DYN1_HUMAN | Dynamin-1
Type:
PROTEIN
Mol. Mass.:
97411.67
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1458576
Residue:
864
Sequence:
MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAPPGVPSRSGQASPSRPESPRPPFDL
  
Inhibitor
Name:
BDBM50147556
Synonyms:
(6Z,8E,10E,14Z)-(5S,12R)-5,12-Dihydroxy-nonadeca-6,8,10,14-tetraenoic acid | CHEMBL418845
Type:
Small organic molecule
Emp. Form.:
C19H30O4
Mol. Mass.:
322.4391
SMILES:
CCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O
Structure:
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