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TargetLysophosphatidic acid receptor Edg-4
LigandBDBM50148436
Substrate/Competitorn/a
Meas. Tech.ChEBML_201449
IC50 270±n/a nM
Citation Hale, JJDoherty, GToth, LMills, SGHajdu, RKeohane, CARosenbach, MMilligan, JShei, GJChrebet, GBergstrom, JCard, DForrest, MSun, SYWest, SXie, HNomura, NRosen, HMandala, S Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists. Bioorg Med Chem Lett14:3501-5 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lysophosphatidic acid receptor Edg-4
Name:Lysophosphatidic acid receptor Edg-4
Synonyms:LPA receptor 2 | LPA-2 | Lysophosphatidic acid receptor 2
Type:PROTEIN
Mol. Mass.:39103.44
Organism:Homo sapiens (Human)
Description:ChEMBL_1451385
Residue:351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50148436
NameBDBM50148436
Synonyms:CHEMBL119382 | {3-[4-(2-Heptyl-2H-tetrazol-5-yl)-benzylamino]-propyl}-phosphonic acid
TypeSmall organic molecule
Emp. Form.C18H30N5O3P
Mol. Mass.395.4363
SMILESCCCCCCCn1nnc(n1)-c1ccc(CNCCCP(O)(O)=O)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a