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TargetLysophosphatidic acid receptor Edg-4
LigandBDBM50148413
Substrate/Competitorn/a
Meas. Tech.ChEBML_201449
IC50 120±n/a nM
Citation Hale, JJDoherty, GToth, LMills, SGHajdu, RKeohane, CARosenbach, MMilligan, JShei, GJChrebet, GBergstrom, JCard, DForrest, MSun, SYWest, SXie, HNomura, NRosen, HMandala, S Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists. Bioorg Med Chem Lett14:3501-5 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Lysophosphatidic acid receptor Edg-4
Name:Lysophosphatidic acid receptor Edg-4
Synonyms:LPA receptor 2 | LPA-2 | Lysophosphatidic acid receptor 2
Type:PROTEIN
Mol. Mass.:39103.44
Organism:Homo sapiens (Human)
Description:ChEMBL_1451385
Residue:351
Sequence:
MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50148413
NameBDBM50148413
Synonyms:CHEMBL116981 | {3-[(4'-Hexyl-biphenyl-4-ylmethyl)-amino]-propyl}-phosphonic acid
TypeSmall organic molecule
Emp. Form.C22H32NO3P
Mol. Mass.389.4681
SMILESCCCCCCc1ccc(cc1)-c1ccc(CNCCCP(O)(O)=O)cc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a