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Target
Mu-type opioid receptor
Ligand
BDBM50151753
Substrate
n/a
Meas. Tech.
ChEBML_305918
IC50
0.540000±n/a nM
Citation
 Weltrowska, G; Lu, Y; Lemieux, C; Chung, NN; Schiller, PW A novel cyclic enkephalin analogue with potent opioid antagonist activity. Bioorg Med Chem Lett 14:4731-3 (2004) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50151753
Synonyms:
1N-[6-carbamoyl-9-(4-nitrobenzyl)-8,11,14-trioxo-(1R,6S,9S)-3,4-dithia-7,10,13-triazacyclotetradecanyl]-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-(2S)-propanamide | CHEMBL184009
Type:
Small organic molecule
Emp. Form.:
C28H35N7O8S2
Mol. Mass.:
661.75
SMILES:
Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H]1CSSC[C@@H](NC(=O)[C@H](Cc2ccc(cc2)[N+]([O-])=O)NC(=O)CNC1=O)C(N)=O
Structure:
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