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Target
Tyrosine-protein kinase
Ligand
BDBM50154585
Substrate
n/a
Meas. Tech.
ChEMBL_302256 (CHEMBL829490)
Kd
800000±n/a nM
Citation
 Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem 47:5405-17 (2004) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase
Synonyms:
Q8CFK4_MOUSE | Tec | Tyrosine-protein kinase TEC
Type:
PROTEIN
Mol. Mass.:
71010.89
Organism:
Mus musculus
Description:
ChEMBL_304473
Residue:
608
Sequence:
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLSYYEGRAEKKYRKGVIDISKIKCVEIVKNDDGVIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR
  
Inhibitor
Name:
BDBM50154585
Synonyms:
CHEMBL187951 | Quinazolin-2-ylamine
Type:
Small organic molecule
Emp. Form.:
C8H7N3
Mol. Mass.:
145.1613
SMILES:
Nc1ncc2ccccc2n1
Structure:
Search PDB for entries with ligand similarity: