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Target
Tyrosine-protein kinase
Ligand
BDBM50154589
Substrate
n/a
Meas. Tech.
ChEMBL_304473 (CHEMBL832689)
EC50
76000±n/a nM
Citation
 Inglis, SR; Stojkoski, C; Branson, KM; Cawthray, JF; Fritz, D; Wiadrowski, E; Pyke, SM; Booker, GW Identification and specificity studies of small-molecule ligands for SH3 protein domains. J Med Chem 47:5405-17 (2004) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase
Synonyms:
Q8CFK4_MOUSE | Tec | Tyrosine-protein kinase TEC
Type:
PROTEIN
Mol. Mass.:
71010.89
Organism:
Mus musculus
Description:
ChEMBL_304473
Residue:
608
Sequence:
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSVLSYYEGRAEKKYRKGVIDISKIKCVEIVKNDDGVIPCQNKFPFQVVHDANTLYIFAPSPQSRDRWVKKLKEEIKNNNNIMIKYHPKFWADGSYQCCRQTEKLAPGCEKYNLFESSIRKTLPPAPEIKKRRPPPPIPPEEENTEEIVVAMYDFQATEAHDLRLERGQEYIILEKNDLHWWRARDKYGWYCRNTNRSKAEQLLRTEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHYHIKETATSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSTKGKNAPTTAGFSYDKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKLTHPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDMLLSMCQDVCEGMEYLERNSFIHRDLAARNCLVNEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYSRFSSKSDVWSFGVLMWEIFTEGRMPFEKNTNYEVVTMVTRGHRLHRPKLASKYLYEVMLRCWQERPEGRPSFEDLLRTIDELVECEETFGR
  
Inhibitor
Name:
BDBM50154589
Synonyms:
6-Chloro-quinolin-2-ylamine | CHEMBL189514
Type:
Small organic molecule
Emp. Form.:
C9H7ClN2
Mol. Mass.:
178.618
SMILES:
Nc1ccc2cc(Cl)ccc2n1
Structure:
Search PDB for entries with ligand similarity: