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Target
Carbonic anhydrase 4
Ligand
BDBM50155537
Substrate
n/a
Meas. Tech.
ChEMBL_302637 (CHEMBL839928)
Ki
84.0±n/a nM
Citation
 Rusconi, S; Innocenti, A; Vullo, D; Mastrolorenzo, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorg Med Chem Lett 14:5763-7 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 4
Synonyms:
CA-IV | CA4 | CAH4_HUMAN | Carbonate dehydratase IV | Carbonic anhydrase | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:
Enzyme
Mol. Mass.:
35037.98
Organism:
Homo sapiens (Human)
Description:
P22748
Residue:
312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLGPMLACLLAGFLR
  
Inhibitor
Name:
BDBM50155537
Synonyms:
CHEMBL363100 | Na3PO4 | Trinatriumphosphat | phosphoric acid trisodium salt | sodium orthophosphate | sodium phosphate | sodium phosphate, tribasic | tertiaeres Natriumphosphat(V) | tertiary sodium phosphate | tribasic sodium orthophosphate | tribasic sodium phosphate
Type:
Small organic molecule
Emp. Form.:
O4P
Mol. Mass.:
94.973
SMILES:
[O-]P([O-])([O-])=O
Structure:
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