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TargetCarbonic anhydrase 4
LigandBDBM50155537
Substrate/Competitorn/a
Meas. Tech.ChEMBL_302637
Ki 84.0±n/a nM
Citation Rusconi, SInnocenti, AVullo, DMastrolorenzo, AScozzafava, ASupuran, CT Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with phosphates, carbamoyl phosphate, and the phosphonate antiviral drug foscarnet. Bioorg Med Chem Lett14:5763-7 (2004) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 4
Name:Carbonic anhydrase
Synonyms:CA-IV | Carbonate dehydratase IV | Carbonic anhydrase 4 (CA IV) | Carbonic anhydrase IV (CA IV)
Type:Enzyme
Mol. Mass.:35037.98
Organism:Homo sapiens (Human)
Description:P22748
Residue:312
Sequence:
MRMLLALLALSAARPSASAESHWCYEVQAESSNYPCLVPVKWGGNCQKDRQSPINIVTTK
AKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSD
LPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLAFLVEAGTQVNEGF
QPLVEALSNIPKPEMSTTMAESSLLDLLPKEEKLRHYFRYLGSLTTPTCDEKVVWTVFRE
PIQLHREQILAFSQKLYYDKEQTVSMKDNVRPLQQLGQRTVIKSGAPGRPLPWALPALLG
PMLACLLAGFLR
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  Blast E-value cutoff:
BDBM50155537
NameBDBM50155537
Synonyms:CHEMBL363100 | Na3PO4 | SODIUM PHOSPHATE | Trinatriumphosphat | phosphoric acid trisodium salt | sodium orthophosphate | sodium phosphate | sodium phosphate, tribasic | tertiaeres Natriumphosphat(V) | tertiary sodium phosphate | tribasic sodium orthophosphate | tribasic sodium phosphate
TypeSmall organic molecule
Emp. Form.O4P
Mol. Mass.94.973
SMILES[O-]P([O-])([O-])=O
Structure
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