Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 3
Ligand
BDBM50160173
Substrate
n/a
Meas. Tech.
ChEMBL_303512 (CHEMBL838626)
Ki
76±n/a nM
Citation
 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhäuser, G; Birke, FW Pyrrolidinohydroquinazolines--a novel class of CCR3 modulators. Bioorg Med Chem Lett 15:669-73 (2005) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 3
Synonyms:
C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor
Type:
Enzyme
Mol. Mass.:
41053.88
Organism:
Homo sapiens (Human)
Description:
P51677
Residue:
355
Sequence:
MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
  
Inhibitor
Name:
BDBM50160173
Synonyms:
3-[1-(2-Iodo-phenyl)-meth-(E)-ylidene]-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-(9Z)-ylideneamine | CHEMBL183461
Type:
Small organic molecule
Emp. Form.:
C18H14IN3
Mol. Mass.:
399.2283
SMILES:
Ic1ccccc1\C=C1/CCn2c1nc1ccccc1c2=N
Structure:
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