Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 3
Ligand
BDBM50160190
Substrate
n/a
Meas. Tech.
ChEMBL_303512 (CHEMBL838626)
Ki
290±n/a nM
Citation
 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhäuser, G; Birke, FW Pyrrolidinohydroquinazolines--a novel class of CCR3 modulators. Bioorg Med Chem Lett 15:669-73 (2005) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 3
Synonyms:
C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor
Type:
Enzyme
Mol. Mass.:
41053.88
Organism:
Homo sapiens (Human)
Description:
P51677
Residue:
355
Sequence:
MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
  
Inhibitor
Name:
BDBM50160190
Synonyms:
8-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-3-cyclopropyl-7,8-dihydro-6H-pyrrolo[1,2-a]thieno[2,3-d]pyrimidin-(4Z)-ylideneamine | CHEMBL183520
Type:
Small organic molecule
Emp. Form.:
C19H16BrN3S
Mol. Mass.:
398.319
SMILES:
Brc1ccccc1\C=C1/CCn2c1nc1scc(C3CC3)c1c2=N
Structure:
Search PDB for entries with ligand similarity: