Reaction Details Report a problem with these data
Target
C-C chemokine receptor type 3
Ligand
BDBM50160196
Substrate
n/a
Meas. Tech.
ChEMBL_303512 (CHEMBL838626)
Ki
7900±n/a nM
Citation
 Anderskewitz, R; Bauer, R; Bodenbach, G; Gester, D; Gramlich, B; Morschhäuser, G; Birke, FW Pyrrolidinohydroquinazolines--a novel class of CCR3 modulators. Bioorg Med Chem Lett 15:669-73 (2005) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 3
Synonyms:
C-C CKR-3 | C-C chemokine receptor type 3 (CCR3) | CC-CKR-3 | CCR-3 | CCR3 | CCR3_HUMAN | CD_antigen=CD193 | CKR3 | CMKBR3 | Eosinophil eotaxin receptor
Type:
Enzyme
Mol. Mass.:
41053.88
Organism:
Homo sapiens (Human)
Description:
P51677
Residue:
355
Sequence:
MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF
  
Inhibitor
Name:
BDBM50160196
Synonyms:
3-[1-(2-Bromo-phenyl)-meth-(E)-ylidene]-1-(4-fluoro-phenyl)-1,2,3,9-tetrahydro-pyrrolo[2,1-b]quinazoline | CHEMBL362032
Type:
Small organic molecule
Emp. Form.:
C24H18BrFN2
Mol. Mass.:
433.316
SMILES:
Fc1ccc(cc1)C1C\C(=C/c2ccccc2Br)C2=Nc3ccccc3CN12 |t:20|
Structure:
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