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Target
Tubulin beta chain [1-43]
Ligand
BDBM50012278
Substrate
n/a
Meas. Tech.
ChEMBL_311916 (CHEMBL834683)
IC50
1000±n/a nM
Citation
 Morita, H; Koyama, K; Sugimoto, Y; Kobayashi, J Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata. Bioorg Med Chem Lett 15:1051-4 (2005) [PubMed]  Article 
Target
Name:
Tubulin beta chain [1-43]
Synonyms:
Beta tubulin | TBB_LEIME
Type:
PROTEIN
Mol. Mass.:
4652.47
Organism:
Leishmania donovani
Description:
ChEMBL_311916
Residue:
43
Sequence:
MREIVSCQAGQCGNQIGSKFWEVIADEHGVDPTGSYQGDSDLQ
  
Inhibitor
Name:
BDBM50012278
Synonyms:
(2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE | CHEMBL159 | VINBLASTINE | VINBLASTINE SULFATE | cid_5388983
Type:
Small organic molecule
Emp. Form.:
C46H58N4O9
Mol. Mass.:
810.9741
SMILES:
CC[C@]1(O)C[C@@H]2CN(C1)CCc1c([nH]c3ccccc13)[C@@](C2)(C(=O)OC)c1cc2c(cc1OC)N(C)[C@@H]1[C@]22CCN3CC=C[C@](CC)([C@@H]23)[C@@H](OC(C)=O)[C@]1(O)C(=O)OC |r,c:48|
Structure:
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