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Target
Prostaglandin D2 receptor 2
Ligand
BDBM50163942
Substrate
n/a
Meas. Tech.
ChEMBL_310535 (CHEMBL834430)
EC50
1.4±n/a nM
Citation
 Kim, S; Bellone, S; Maxey, KM; Powell, WS; Lee, GJ; Rokach, J Synthesis of 15R-PGD2: a potential DP2 receptor agonist. Bioorg Med Chem Lett 15:1873-6 (2005) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor 2
Synonyms:
CD_antigen=CD294 | CRTH2 | Chemoattractant Receptor-homologous molecule expressed on T-helper type 2 cells (CRTH2) | Chemoattractant receptor-homologous molecule expressed on Th2 cells | Chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2) | DL1R | G protein-coupled receptor 44 | G-protein coupled receptor 44 | GPR44 | PD2R2_HUMAN | PTGDR2 | Prostaglandin D2 | Prostaglandin D2 receptor 2 | Prostaglandin D2 receptor 2 (PGD2)
Type:
Enzyme
Mol. Mass.:
43295.45
Organism:
Homo sapiens (Human)
Description:
Q9Y5Y4
Residue:
395
Sequence:
MSANATLKPLCPILEQMSRLQSHSNTSIRYIDHAAVLLHGLASLLGLVENGVILFVVGCRMRQTVVTTWVLHLALSDLLASASLPFFTYFLAVGHSWELGTTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVVRPVWAQNHRTVAAAHKVCLVLWALAVLNTVPYFVFRDTISRLDGRIMCYYNVLLLNPGPDRDATCNSRQVALAVSKFLLAFLVPLAIIASSHAAVSLRLQHRGRRRPGRFVRLVAAVVAAFALCWGPYHVFSLLEARAHANPGLRPLVWRGLPFVTSLAFFNSVANPVLYVLTCPDMLRKLRRSLRTVLESVLVDDSELGGAGSSRRRRTSSTARSASPLALCSRPEEPRGPARLLGWLLGSCAASPQTGPLNRALSSTSS
  
Inhibitor
Name:
BDBM50163942
Synonyms:
(Z)-7-[(1R,4S,5R)-5-Hydroxy-2-((R)-3-hydroxy-3-methyl-oct-1-enyl)-3-oxo-cyclopentyl]-hept-5-enoic acid | (Z)-7-[(1R,4S,5S)-5-Hydroxy-2-((R)-3-hydroxy-3-methyl-oct-1-enyl)-3-oxo-cyclopentyl]-hept-5-enoic acid | CHEMBL180344
Type:
Small organic molecule
Emp. Form.:
C21H34O5
Mol. Mass.:
366.4917
SMILES:
CCCCC[C@@](C)(O)\C=C\[C@@H]1[C@@H](C\C=C\CCCC(O)=O)[C@@H](O)CC1=O
Structure:
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