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Target
Sex hormone-binding globulin
Ligand
BDBM50166034
Substrate
n/a
Meas. Tech.
ChEMBL_305616 (CHEMBL829479)
IC50
13600±n/a nM
Citation
 Cherkasov, A; Shi, Z; Fallahi, M; Hammond, GL Successful in silico discovery of novel nonsteroidal ligands for human sex hormone binding globulin. J Med Chem 48:3203-13 (2005) [PubMed]  Article 
Target
Name:
Sex hormone-binding globulin
Synonyms:
SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein
Type:
PROTEIN
Mol. Mass.:
43780.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_466706
Residue:
402
Sequence:
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
  
Inhibitor
Name:
BDBM50166034
Synonyms:
1-(2,4-Dihydroxy-phenyl)-2-(4-hydroxy-phenyl)-ethanone | 2,4,4'-Trihydroxydeoxybenzoin | 2,4,4'-terthydroxydeoxybenzoin | CHEMBL193200
Type:
Small organic molecule
Emp. Form.:
C14H12O4
Mol. Mass.:
244.2427
SMILES:
Oc1ccc(CC(=O)c2ccc(O)cc2O)cc1
Structure:
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