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Target
Gamma-hydroxybutyrate receptor
Ligand
BDBM50168281
Substrate
n/a
Meas. Tech.
ChEMBL_306316 (CHEMBL827761)
IC50
4500±n/a nM
Citation
 Chen, W; Wu, H; Hernandez, RJ; Mehta, AK; Ticku, MK; France, CP; Coop, A Ethers of 3-hydroxyphenylacetic acid as selective gamma-hydroxybutyric acid receptor ligands. Bioorg Med Chem Lett 15:3201-2 (2005) [PubMed]  Article 
Target
Name:
Gamma-hydroxybutyrate receptor
Synonyms:
Gamma hydroxybutyric, GHB | Gamma-hydroxybutyrate receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
56171.11
Organism:
RAT
Description:
Gamma hydroxybutyric, GHB 0 RAT::Q6RY99
Residue:
512
Sequence:
MRAAAAGLGPGRLHAWAARRGLGRFPARVPRAAGGRSPCPASISNSRTLRLAAAGNTFCLASTLSSGCWEPCSWPSASGPGVRRAFFPTSQGGQIQGGLDPVWLFVVIGGIMSVLGFAGCIGALRENTFLLKFFSVFLGLIFFLELAAGILAFVFKDWIRDQLNLFINNNVKAYRDDIDLQNLIDFAQEYWSCCGARGPNDWNLNIRTSTALTSNPSRERCGVPFFCWVRTLRKTSQYPCGYTSAQTELEHKIHLHQSWWPFEKWLKKPDGWPGLGAIASFKMGIAGPNPRSTSRQERPTGKLPGVMATCLAHRAVVGASKDALPHSQWQGLWDVCYDLSPRLCEHGTQEATEAGLGLNWGCTGAGLGLFTTELCVWGVHMCVCVCVCVCVRVCLCLCVRVRGMHVCALVSTPGVSTPLLVRWWPFQSFKGDGARRVGHVPASPSLLWDVSLCGLGACCLRPLHIHHDLEPAWSSPWPQCHSLEMGPRILSVSLSRLPLRTHTWQDGYERLN
  
Inhibitor
Name:
BDBM50168281
Synonyms:
CHEMBL189853 | [3-(3-Phenyl-propoxy)-phenyl]-acetic acid
Type:
Small organic molecule
Emp. Form.:
C17H18O3
Mol. Mass.:
270.323
SMILES:
OC(=O)Cc1cccc(OCCCc2ccccc2)c1
Structure:
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