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Target
Melanin-concentrating hormone receptor 1
Ligand
BDBM50168524
Substrate
n/a
Meas. Tech.
ChEMBL_306753 (CHEMBL830898)
IC50
4300±n/a nM
Citation
 Vasudevan, A; Verzal, MK; Wodka, D; Souers, AJ; Blackburn, C; Che, JL; Lai, S; Brodjian, S; Falls, DH; Dayton, BD; Govek, E; Daniels, T; Geddes, B; Marsh, KC; Hernandez, LE; Collins, CA; Kym, PR Identification of aminopiperidine benzamides as MCHr1 antagonists. Bioorg Med Chem Lett 15:3412-6 (2005) [PubMed]  Article 
Target
Name:
Melanin-concentrating hormone receptor 1
Synonyms:
Gpr24 | MCHR1_MOUSE | Mchr1 | Slc1
Type:
PROTEIN
Mol. Mass.:
39133.74
Organism:
Mus musculus
Description:
ChEMBL_818502
Residue:
353
Sequence:
MDLQASLLSTGPNASNISDGQDNFTLAGPPPRTRSVSYINIIMPSVFGTICLLGIVGNSTVIFAVVKKSKLHWCSNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSMATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVKILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKPAAQGQLRTVSNAQTADEERTESKGT
  
Inhibitor
Name:
BDBM50168524
Synonyms:
CHEMBL187553 | N-(1-Benzo[1,3]dioxol-5-ylmethyl-piperidin-3-yl)-3,5-dihydroxy-benzamide
Type:
Small organic molecule
Emp. Form.:
C20H22N2O5
Mol. Mass.:
370.3991
SMILES:
Oc1cc(O)cc(c1)C(=O)NC1CCCN(Cc2ccc3OCOc3c2)C1
Structure:
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