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Target
Dual specificity protein phosphatase 3
Ligand
BDBM50168877
Substrate
n/a
Meas. Tech.
ChEMBL_304945 (CHEMBL826974)
IC50
130000±n/a nM
Citation
 Cutshall, NS; O'Day, C; Prezhdo, M Rhodanine derivatives as inhibitors of JSP-1. Bioorg Med Chem Lett 15:3374-9 (2005) [PubMed]  Article 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM50168877
Synonyms:
2-Hydroxy-5-{4-oxo-5-[1-phenyl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-benzoic acid | CHEMBL185578
Type:
Small organic molecule
Emp. Form.:
C17H11NO4S2
Mol. Mass.:
357.404
SMILES:
OC(=O)c1cc(ccc1O)N1C(=S)S\C(=C/c2ccccc2)C1=O
Structure:
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