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Target
Adenosine receptor A2a
Ligand
BDBM50171759
Substrate
n/a
Meas. Tech.
ChEMBL_320862 (CHEMBL884787)
Ki
35±n/a nM
Citation
 Manera, C; Betti, L; Cavallini, T; Giannaccini, G; Martinelli, A; Ortore, G; Saccomanni, G; Trincavelli, L; Tuccinardi, T; Ferrarini, PL 1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors. Bioorg Med Chem Lett 15:4604-10 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A2a
Synonyms:
A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44716.46
Organism:
Homo sapiens (Human)
Description:
P29274
Residue:
412
Sequence:
MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNGYALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
  
Inhibitor
Name:
BDBM50171759
Synonyms:
7-Methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid (furan-2-ylmethyl)-amide | CHEMBL196138
Type:
Small organic molecule
Emp. Form.:
C15H13N3O3
Mol. Mass.:
283.282
SMILES:
Cc1ccc2c(O)c(cnc2n1)C(=O)NCc1ccco1
Structure:
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