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Target
Abscisic acid 8'-hydroxylase 3
Ligand
BDBM50174072
Substrate
n/a
Meas. Tech.
ChEMBL_326985 (CHEMBL868744)
Ki
170±n/a nM
Citation
 Ueno, K; Yoneyama, H; Saito, S; Mizutani, M; Sakata, K; Hirai, N; Todoroki, Y A lead compound for the development of ABA 8'-hydroxylase inhibitors. Bioorg Med Chem Lett 15:5226-9 (2005) [PubMed]  Article 
Target
Name:
Abscisic acid 8'-hydroxylase 3
Synonyms:
ABAH3_ARATH | CYP707A3 | Cytochrome P450 monooxygenase
Type:
PROTEIN
Mol. Mass.:
52380.10
Organism:
Arabidopsis thaliana
Description:
ChEMBL_358214
Residue:
463
Sequence:
MDFSGLFLTLSAAALFLCLLRFIAGVRRSSSTKLPLPPGTMGYPYVGETFQLYSQDPNVFFAAKQRRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFKPTFPASKERMLGKQAIFFHQGDYHSKLRKLVLRAFMPDAIRNMVPHIESIAQESLNSWDGTQLNTYQEMKTYTFNVALISILGKDEVYYREDLKRCYYILEKGYNSMPINLPGTLFHKAMKARKELAQILANILSKRRQNPSSHTDLLGSFMEDKAGLTDEQIADNIIGVIFAARDTTASVLTWILKYLADNPTVLEAVTEEQMAIRKDKKEGESLTWEDTKKMPLTYRVIQETLRAATILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHNADIFSDPGKFDPSRFEVAPKPNTFMPFGSGIHSCPGNELAKLEISVLIHHLTTKYRWSIVGPSDGIQYGPFALPQNGLPIALERKP
  
Inhibitor
Name:
BDBM50174072
Synonyms:
(+)-8',8'-difluoro-ABA | CHEMBL199709
Type:
Small organic molecule
Emp. Form.:
C15H18F2O4
Mol. Mass.:
300.2978
SMILES:
CC(C=C[C@@]1(O)C(C)=CC(=O)C[C@]1(C)C(F)F)=CC(O)=O |w:17.18,2.1,c:7|
Structure:
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