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Target
Cannabinoid receptor 2
Ligand
BDBM50176977
Substrate
n/a
Meas. Tech.
ChEMBL_430952 (CHEMBL914894)
Ki
0.34±n/a nM
Citation
 Murineddu, G; Ruiu, S; Loriga, G; Manca, I; Lazzari, P; Reali, R; Pani, L; Toma, L; Pinna, GA Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide. J Med Chem 48:7351-62 (2005) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50176977
Synonyms:
1,4-dihydroindeno[1,2-c]-pyrazole | 6-chloro-1-(2',4-dichlorophenyl)-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide | CHEMBL218957
Type:
Small organic molecule
Emp. Form.:
C22H19Cl3N4O
Mol. Mass.:
461.771
SMILES:
Clc1ccc-2c(Cc3c(nn(c-23)-c2ccc(Cl)cc2Cl)C(=O)NN2CCCCC2)c1
Structure:
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