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Target
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Ligand
BDBM50177318
Substrate
n/a
Meas. Tech.
ChEMBL_331861 (CHEMBL865879)
IC50
220±n/a nM
Citation
 Cho, SY; Baek, JY; Han, SS; Kang, SK; Ha, JD; Ahn, JH; Lee, JD; Kim, KR; Cheon, HG; Rhee, SD; Yang, SD; Yon, GH; Pak, CS; Choi, JK PTP-1B inhibitors: cyclopenta[d][1,2]-oxazine derivatives. Bioorg Med Chem Lett 16:499-502 (2005) [PubMed]  Article 
Target
Name:
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
Synonyms:
PP1G_HUMAN | PPP1CC | Serine/threonine protein phosphatase PP1-gamma catalytic subunit
Type:
PROTEIN
Mol. Mass.:
36983.39
Organism:
Homo sapiens (Human)
Description:
ChEMBL_473188
Residue:
323
Sequence:
MADLDKLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAEKKKPNATRPVTPPRGMITKQAKK
  
Inhibitor
Name:
BDBM50177318
Synonyms:
2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxazin-4-yl)phenoxy)acetic acid | CHEMBL200117
Type:
Small organic molecule
Emp. Form.:
C36H43NO5
Mol. Mass.:
569.7303
SMILES:
CCCCCCCCCCCCCCc1ccc(cc1)C(=O)c1ccc2c(nocc12)-c1ccc(OCC(O)=O)cc1
Structure:
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