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Target
Voltage-dependent calcium channel subunit alpha-2/delta-1
Ligand
BDBM50179721
Substrate
n/a
Meas. Tech.
ChEMBL_335548 (CHEMBL859414)
Ki
180±n/a nM
Citation
 Mortell, KH; Anderson, DJ; Lynch, JJ; Nelson, SL; Sarris, K; McDonald, H; Sabet, R; Baker, S; Honore, P; Lee, CH; Jarvis, MF; Gopalakrishnan, M Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett 16:1138-41 (2006) [PubMed]  Article 
Target
Name:
Voltage-dependent calcium channel subunit alpha-2/delta-1
Synonyms:
CA2D1_MOUSE | Cacna2 | Cacna2d1 | Voltage-gated calcium channel alpha2/delta subunit 1
Type:
PROTEIN
Mol. Mass.:
124608.02
Organism:
Mus musculus
Description:
ChEMBL_335548
Residue:
1103
Sequence:
MAAGCLLALTLTLFQSGLIGPSSEEPFPSPVTIKSWVDKMQEDLVTLAKTASGVTQLADIYEKYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLAMEAEKVQAAHQWREDFASNEVVYYNAKDDLDPERNESEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVLNELNWTSALDEVFKRNRDEDPTLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRRRPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRANCNKIIMLFTDGGEERAQEIFAKYNKDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPSIGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALELGLVITGTLPVFNVTGQSENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLHPNLQPKPIGVGIPTINLRKRRPNVQNPKSQEPVTLDFLDAELENEIKVEIRNKMIDGESGEKTFRTLVKSQDERYIDKGNRTYTWTPVNGTDYSLALVLPTYSFYYIKAKLEETITQARYSETLKPDNFEESGYTFIAPREYCNDLKPSDNNTEFLLNFNEFIDRKTPNNPSCNTDLINRILLDAGFTNELVQNYWSKQKNIKGVKARFVVTDGGITRVYPKEAGENWQENPETYEDSFYKRSLDNDNYVFTAPYFNKSGPGAYESGIMVSKAVELYIQGKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMANHDDYTNQIGRFFGEIDPSMMRHLVNISLYAFNKSYDYQSVCDPGAAPKQGAGHRSAYVPSIADILQIGWWATAAAWSILQQLLLSLTFPRLLEAVEMEEDDFTASLSKQSCITEQTQYFFKNDTKSFSGLLDCGNCSRIFHVEKLMNTNLVFIMVESKGTCPCDTRLLMQAEQTSDGPDPCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGLNPSLWSIFGLQFILLWLVSGSRHYLL
  
Inhibitor
Name:
BDBM50179721
Synonyms:
(2S)-amino(phenyl)ethanoic acid | (S)-phenylglycine | CHEMBL378605
Type:
Small organic molecule
Emp. Form.:
C8H9NO2
Mol. Mass.:
151.1626
SMILES:
N[C@H](C(O)=O)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: