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Target
Mu-type opioid receptor
Ligand
BDBM50182944
Substrate
n/a
Meas. Tech.
ChEMBL_349389 (CHEMBL865710)
EC50
100±n/a nM
Citation
 Breslin, HJ; Cai, C; Miskowski, TA; Coutinho, SV; Zhang, SP; Hornby, P; He, W Identification of potent phenyl imidazoles as opioid receptor agonists. Bioorg Med Chem Lett 16:2505-8 (2006) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50182944
Synonyms:
4-((S)-2-amino-3-oxo-3-((S)-2-(4-phenyl-1H-imidazol-2-yl)piperidin-1-yl)propyl)benzamide | CHEMBL204996
Type:
Small organic molecule
Emp. Form.:
C24H27N5O2
Mol. Mass.:
417.5035
SMILES:
N[C@@H](Cc1ccc(cc1)C(N)=O)C(=O)N1CCCC[C@H]1c1nc(c[nH]1)-c1ccccc1
Structure:
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