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Target
Glucagon receptor
Ligand
BDBM50183180
Substrate
n/a
Meas. Tech.
ChEMBL_355175 (CHEMBL853195)
IC50
35000±n/a nM
Citation
 Kumar, A; Pathak, SR; Ahmad, P; Ray, S; Tewari, P; Srivastava, AK Novel substituted naphthalen-1-yl-methanone derivatives as anti-hyperglycemic agents. Bioorg Med Chem Lett 16:2719-23 (2006) [PubMed]  Article 
Target
Name:
Glucagon receptor
Synonyms:
GCGR | GL-R | GLR_HUMAN | Glucagon Receptor (GCGR) | Glucagon receptor (GlucR)
Type:
Enzyme
Mol. Mass.:
54026.92
Organism:
Homo sapiens (Human)
Description:
P47871
Residue:
477
Sequence:
MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNRTFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQCQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRLGKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
  
Inhibitor
Name:
BDBM50183180
Synonyms:
4-[2-(4-methoxybenzylamino-propoxy)-phenyl]-naphthalen-1yl-methanone | CHEMBL379600
Type:
Small organic molecule
Emp. Form.:
C27H25NO3
Mol. Mass.:
411.4923
SMILES:
COc1ccc(NCCCOc2ccc(cc2)C(=O)c2cccc3ccccc23)cc1
Structure:
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