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Target
UDP-glucuronosyltransferase 2B17
Ligand
BDBM50183618
Substrate
n/a
Meas. Tech.
ChEMBL_339080 (CHEMBL867716)
IC50
162000±n/a nM
Citation
 Bichlmaier, I; Siiskonen, A; Finel, M; Yli-Kauhaluoma, J Stereochemical sensitivity of the human UDP-glucuronosyltransferases 2B7 and 2B17. J Med Chem 49:1818-27 (2006) [PubMed]  Article 
Target
Name:
UDP-glucuronosyltransferase 2B17
Synonyms:
UDB17_HUMAN | UGT2B17
Type:
PROTEIN
Mol. Mass.:
61109.88
Organism:
Homo sapiens (Human)
Description:
ChEMBL_436440
Residue:
530
Sequence:
MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTLFETMGKAEMWLIRTYWDFEFPRPFLPNVDFVGGLHCKPAKPLPKEMEEFVQSSGENGIVVFSLGSMISNMSEESANMIASALAQIPQKVLWRFDGKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAKTGKKKKRD
  
Inhibitor
Name:
BDBM50183618
Synonyms:
(+/-)-(R)-7-Methoxy-1-tetralol | CHEMBL206379
Type:
Small organic molecule
Emp. Form.:
C11H14O2
Mol. Mass.:
178.2277
SMILES:
COc1ccc2CCC[C@@H](O)c2c1
Structure:
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