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TargetAlpha-L-fucosidase I
LigandBDBM50186736
Substrate/Competitorn/a
Meas. Tech.ChEMBL_353427
pH6.8±n/a
Ki>1000000±n/a nM
Commentsextracted
Citation Wang, RWQiu, XLBols, MOrtega-Caballero, FQing, FL Synthesis and biological evaluation of glycosidase inhibitors: gem-difluoromethylenated nojirimycin analogues. J Med Chem49:2989-97 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Alpha-L-fucosidase I
Name:Alpha-L-fucosidase I
Synonyms:Alpha-L-fucoside fucohydrolase | Tissue alpha-L-fucosidase
Type:PROTEIN
Mol. Mass.:53690.69
Organism:Homo sapiens (Human)
Description:ChEMBL_34088
Residue:466
Sequence:
MRAPGMRSRPAGPALLLLLLFLGAAESVRRAQPPRRYTPDWPSLDSRPLPAWFDEAKFGV
FIHWGVFSVPAWGSEWFWWHWQGEGRPQYQRFMRDNYPPGFSYADFGPQFTARFFHPEEW
ADLFQAAGAKYVVLTTKHHEGFTNWPSPVSWNWNSKDVGPHRDLVGELGTALRKRNIRYG
LYHSLLEWFHPLYLLDKKNGFKTQHFVSAKTMPELYDLVNSYKPDLIWSDGEWECPDTYW
NSTNFLSWLYNDSPVKDEVVVNDRWGQNCSCHHGGYYNCEDKFKPQSLPDHKWEMCTSID
KFSWGYRRDMALSDVTEESEIISELVQTVSLGGNYLLNIGPTKDGLIVPIFQERLLAVGK
WLSINGEAIYASKPWRVQWEKNTTSVWYTSKGSAVYAIFLHWPENGVLNLESPITTSTTK
ITMLGIQGDLKWSTDPDKGLFISLPQLPPSAVPAEFAWTIKLTGVK
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  Blast E-value cutoff:
BDBM50186736
NameBDBM50186736
Synonyms:CHEMBL380311 | L-1,4-dideoxy-4,4-difluorogulonojirimycin
TypeSmall organic molecule
Emp. Form.C6H11F2NO3
Mol. Mass.183.1532
SMILESOC[C@@H]1NC[C@@H](O)[C@@H](O)C1(F)F
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a