Reaction Details Report a problem with these data
Target
S-ribosylhomocysteine lyase
Ligand
BDBM50186745
Substrate
n/a
Meas. Tech.
ChEMBL_353578 (CHEMBL861693)
Ki
473000±n/a nM
Citation
 Shen, G; Rajan, R; Zhu, J; Bell, CE; Pei, D Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase. J Med Chem 49:3003-11 (2006) [PubMed]  Article 
Target
Name:
S-ribosylhomocysteine lyase
Synonyms:
LUXS_BACSU | luxS | ytjB
Type:
PROTEIN
Mol. Mass.:
17709.00
Organism:
Bacillus subtilis
Description:
ChEMBL_764478
Residue:
157
Sequence:
MPSVESFELDHNAVVAPYVRHCGVHKVGTDGVVNKFDIRFCQPNKQAMKPDTIHTLEHLLAFTIRSHAEKYDHFDIIDISPMGCQTGYYLVVSGEPTSAEIVDLLEDTMKEAVEITEIPAANEKQCGQAKLHDLEGAKRLMRFWLSQDKEELLKVFG
  
Inhibitor
Name:
BDBM50186745
Synonyms:
(S)-2-amino-6-(4-mercaptobutanamido)hexanoic acid | CHEMBL438441
Type:
Small organic molecule
Emp. Form.:
C10H20N2O3S
Mol. Mass.:
248.342
SMILES:
N[C@@H](CCCCNC(=O)CCCS)C(O)=O
Structure:
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