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Target
S-ribosylhomocysteine lyase
Ligand
BDBM50186746
Substrate
n/a
Meas. Tech.
ChEMBL_353579 (CHEMBL861694)
Ki
12700±n/a nM
Citation
 Shen, G; Rajan, R; Zhu, J; Bell, CE; Pei, D Design and synthesis of substrate and intermediate analogue inhibitors of S-ribosylhomocysteinase. J Med Chem 49:3003-11 (2006) [PubMed]  Article 
Target
Name:
S-ribosylhomocysteine lyase
Synonyms:
LUXS_ECOLI | luxS | ygaG
Type:
PROTEIN
Mol. Mass.:
19410.45
Organism:
Escherichia coli (strain K12)
Description:
ChEMBL_353579
Residue:
171
Sequence:
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI
  
Inhibitor
Name:
BDBM50186746
Synonyms:
(2S)-2-AMINO-4-[(2R,3R)-2,3-DIHYDROXY-3-N-HYDROXYCARBAMOYL-PROPYLMERCAPTO]BUTYRIC ACID | (2S)-2-amino-4-[(2R,3R)-2,3-dihydroxy-3-N-hydroxycarbamoylpropylmercapto]butyric acid | CHEMBL208091
Type:
Small organic molecule
Emp. Form.:
C8H16N2O6S
Mol. Mass.:
268.287
SMILES:
N[C@@H](CCSC[C@H](O)[C@@H](O)C(=O)NO)C(O)=O
Structure:
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