Reaction Details Report a problem with these data
Target
Galanin receptor type 3
Ligand
BDBM50187911
Substrate
n/a
Meas. Tech.
ChEMBL_384498 (CHEMBL866716)
Ki
5±n/a nM
Citation
 Konkel, MJ; Packiarajan, M; Chen, H; Topiwala, UP; Jimenez, H; Talisman, IJ; Coate, H; Walker, MW Amino substituted analogs of 1-phenyl-3-phenylimino-2-indolones with potent galanin Gal3 receptor binding affinity and improved solubility. Bioorg Med Chem Lett 16:3950-4 (2006) [PubMed]  Article 
Target
Name:
Galanin receptor type 3
Synonyms:
GALNR3 | GALR3 | GALR3_HUMAN | Galanin R3 | Galanin receptor 3 | Galanin receptor type 3
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39599.97
Organism:
Homo sapiens (Human)
Description:
Galanin R3 GALR3 HUMAN::O60755
Residue:
368
Sequence:
MADAQNISLDSPGSVGAVAVPVVFALIFLLGTVGNGLVLAVLLQPGPSAWQEPGSTTDLFILNLAVADLCFILCCVPFQATIYTLDAWLFGALVCKAVHLLIYLTMYASSFTLAAVSVDRYLAVRHPLRSRALRTPRNARAAVGLVWLLAALFSAPYLSYYGTVRYGALELCVPAWEDARRRALDVATFAAGYLLPVAVVSLAYGRTLRFLWAAVGPAGAAAAEARRRATGRAGRAMLAVAALYALCWGPHHALILCFWYGRFAFSPATYACRLASHCLAYANSCLNPLVYALASRHFRARFRRLWPCGRRRRHRARRALRRVRPASSGPPGCPGDARPSGRLLAGGGQGPEPREGPVHGGEAARGPE
  
Inhibitor
Name:
BDBM50187911
Synonyms:
1,3-dihydro-1-[3-(2-pyrrolidinylethoxy)phenyl]-3-[[3-(trifluoromethyl)phenyl]imino]-2H-indol-2-one | CHEMBL209497
Type:
Small organic molecule
Emp. Form.:
C27H24F3N3O2
Mol. Mass.:
479.4936
SMILES:
FC(F)(F)c1cccc(c1)\N=C1\C(=O)N(c2ccccc12)c1cccc(OCCN2CCCC2)c1
Structure:
Search PDB for entries with ligand similarity: