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Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50191992
Substrate
n/a
Meas. Tech.
ChEMBL_392530 (CHEMBL864291)
Ki
200±n/a nM
Citation
 Sun, Q; Law, A; Crowder, MW; Geysen, HM Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis. Bioorg Med Chem Lett 16:5169-75 (2006) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50191992
Synonyms:
(2R)-2-(2-(5-chloro-1H-indole-2-carboxamido)-4-mercaptobutanamido)-3-phenylpropanoic acid | CHEMBL215297
Type:
Small organic molecule
Emp. Form.:
C22H22ClN3O4S
Mol. Mass.:
459.946
SMILES:
OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc2cc(Cl)ccc2[nH]1
Structure:
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