Reaction Details Report a problem with these data
Target
Metallo-beta-lactamase L1 type 3
Ligand
BDBM50192001
Substrate
n/a
Meas. Tech.
ChEMBL_392530 (CHEMBL864291)
Ki
390±n/a nM
Citation
 Sun, Q; Law, A; Crowder, MW; Geysen, HM Homo-cysteinyl peptide inhibitors of the L1 metallo-beta-lactamase, and SAR as determined by combinatorial library synthesis. Bioorg Med Chem Lett 16:5169-75 (2006) [PubMed]  Article 
Target
Name:
Metallo-beta-lactamase L1 type 3
Synonyms:
BLA1_STEMA | Beta-lactamase L1
Type:
PROTEIN
Mol. Mass.:
30803.13
Organism:
Stenotrophomonas maltophilia
Description:
ChEMBL_1500319
Residue:
290
Sequence:
MRSTLLAFALAVALPAAHTSAAEVPLPQLRAYTVDASWLQPMAPLQIADHTWQIGTEDLTALLVQTPDGAVLLDGGMPQMASHLLDNMKARGVTPRDLRLILLSHAHADHAGPVAELKRRTGAKVAANAESAVLLARGGSDDLHFGDGITYPPANADRIVMDGEVITVGGIVFTAHFMAGHTPGSTAWTWTDTRNGKPVRIAYADSLSAPGYQLQGNPRYPHLIEDYRRSFATVRALPCDVLLTPHPGASNWDYAAGARAGAKALTCKAYADAAEQKFDGQLAKETAGAR
  
Inhibitor
Name:
BDBM50192001
Synonyms:
(2R)-2-(2-(2-(4-acetamido-3-nitrophenyl)acetamido)-4-mercaptobutanamido)-3-phenylpropanoic acid | CHEMBL387243
Type:
Small organic molecule
Emp. Form.:
C23H26N4O7S
Mol. Mass.:
502.54
SMILES:
CC(=O)Nc1ccc(CC(=O)NC(CCS)C(=O)N[C@H](Cc2ccccc2)C(O)=O)cc1[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: