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Target
Transporter
Ligand
BDBM50193219
Substrate
n/a
Meas. Tech.
ChEMBL_392661 (CHEMBL863114)
Ki
>50000±n/a nM
Citation
 Bois, F; Baldwin, RM; Kula, NS; Baldessarini, RJ; Al Tikriti, M; Innis, RB; Tamagnan, GD Synthesis and monoamine transporter affinity of 2beta-carbomethoxy-3beta-(4'-p-substituted phenyl)-piperidine analogs of cocaine. Bioorg Med Chem Lett 16:5222-5 (2006) [PubMed]  Article 
Target
Name:
Transporter
Synonyms:
Monoamine transporters; Norepininephrine & dopamine | Norepinephrine Monoamine transporters
Type:
PROTEIN
Mol. Mass.:
66787.87
Organism:
Rattus norvegicus
Description:
ChEMBL_1463061
Residue:
597
Sequence:
MVTRTRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYVSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLLALEIELSSLQSFVITSCPIDPLLSSFLFISCQKTLVFKKSGPAPLI
  
Inhibitor
Name:
BDBM50193219
Synonyms:
(3S,4S)-methyl 1-methyl-4-(4-(thiophen-2-yl)phenyl)piperidine-3-carboxylate | CHEMBL214618
Type:
Small organic molecule
Emp. Form.:
C18H21NO2S
Mol. Mass.:
315.43
SMILES:
COC(=O)[C@@H]1CN(C)CC[C@@H]1c1ccc(cc1)-c1cccs1
Structure:
Search PDB for entries with ligand similarity: