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TargetCyclin-dependent kinase 2
LigandBDBM5485
Substrate/Competitorn/a
Meas. Tech.ChEMBL_383686
Ki 1200±n/a nM
Citation Heady, LFernandez-Serra, MMancera, RLJoyce, SVenkitaraman, ARArtacho, ESkylaris, CKCiacchi, LCPayne, MC Novel structural features of CDK inhibition revealed by an ab initio computational method combined with dynamic simulations. J Med Chem49:5141-53 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Cyclin-dependent kinase 2
Name:CDK2/Bovine cyclin A
Synonyms:CDK2 | CDK2-Kinase | Cell division protein kinase 2 | Cyclin-dependent kinase 2 (CDK2) | p33 protein kinase
Type:Enzyme Subunit
Mol. Mass.:33938.17
Organism:Homo sapiens (Human)
Description:P24941
Residue:298
Sequence:
MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH
PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS
HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY
STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF
PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL
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  Blast E-value cutoff:
BDBM5485
NameBDBM5485
Synonyms:6-(cyclohexylmethoxy)-9H-purin-2-amine | CHEMBL269881 | NU2058
TypeSmall organic molecule
Emp. Form.C12H17N5O
Mol. Mass.247.2963
SMILESNc1nc(OCC2CCCCC2)c2[nH]cnc2n1
Structure
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