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Target
Adenosine receptor A1
Ligand
BDBM50196010
Substrate
n/a
Meas. Tech.
ChEMBL_431897 (CHEMBL917395)
Ki
11±n/a nM
Citation
 Giorgi, I; Bianucci, AM; Biagi, G; Livi, O; Scartoni, V; Leonardi, M; Pietra, D; Coi, A; Massarelli, I; Nofal, FA; Fiamingo, FL; Anastasi, P; Giannini, G Synthesis, biological activity and molecular modelling of new trisubstituted 8-azaadenines with high affinity for A1 adenosine receptors. Eur J Med Chem 42:1-9 (2007) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36602.99
Organism:
BOVINE
Description:
ADENOSINE 0 BOVINE::P28190
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
  
Inhibitor
Name:
BDBM50196010
Synonyms:
3-(2-fluorobenzyl)-N-ethyl-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine | CHEMBL227677
Type:
Small organic molecule
Emp. Form.:
C19H17FN6
Mol. Mass.:
348.3769
SMILES:
CCNc1nc(nc2n(Cc3ccccc3F)nnc12)-c1ccccc1
Structure:
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