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TargetThyrotropin-releasing hormone receptor 2
LigandBDBM50072394
Substrate/Competitorn/a
Meas. Tech.ChEMBL_431932
Ki 10±n/a nM
Citation Kaur, NMonga, VLu, XGershengorn, MCJain, R Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1. Bioorg Med Chem15:433-43 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thyrotropin-releasing hormone receptor 2
Name:Thyrotropin-releasing hormone receptor 2
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39044.21
Organism:Rattus norvegicus
Description:ChEMBL_532304
Residue:352
Sequence:
MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCY
LVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVER
YIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRG
LYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCS
RAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAV
NPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50072394
NameBDBM50072394
Synonyms:1-[3-(1H-4-imidazolyl)-2-(5-oxotetrahydro-1H-2-pyrrolylcarboxamido)propanoyl]tetrahydro-1H-2-pyrrolecarboxamide | A-38579 | ABBOTT-38579 | PROTIRELIN
TypeSmall organic molecule
Emp. Form.C16H22N6O4
Mol. Mass.362.3837
SMILESNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1 |r|
Structure
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n/a