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TargetThyrotropin-releasing hormone receptor 2
LigandBDBM50196452
Substrate/Competitorn/a
Meas. Tech.ChEMBL_431932
Ki>100000±n/a nM
Citation Kaur, NMonga, VLu, XGershengorn, MCJain, R Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1. Bioorg Med Chem15:433-43 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thyrotropin-releasing hormone receptor 2
Name:Thyrotropin-releasing hormone receptor 2
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:39044.21
Organism:Rattus norvegicus
Description:ChEMBL_532304
Residue:352
Sequence:
MDGPSNVSLIHGDTTLGLPEYKVVSVFLVLLVCTLGIVGNAMVILVVLTSRDMHTPTNCY
LVSLALADLLVLLAAGLPNVSDSLVGHWIYGRAGCLGITYFQYLGINVSSFSILAFTVER
YIAICHPLRAQTVCTVARAKRIIAGIWGVTSLYCLLWFFLVDLNVRDNQRLECGYKVPRG
LYLPIYLLDFAVFFIGPLLVTLVLYGLIGRILFQSPLSQEAWQKERQPHGQSEAAPGNCS
RAKSSRKQATRMLAVVVLLFAVLWTPYRTLVLLNSFVAQPFLDPWVLLFCRTCVYTNSAV
NPVVYSLMSQKFRAAFLKLCWCRAAGPQRRAARVLTSNYSAAQETSEGTEKM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50196452
NameBDBM50196452
Synonyms:(2S)-1-[(2S)-2-(1S)-3-oxocyclopentylcarboxamido]-3-(2-cyclohexyl-1H-imidazolyl)propanoyl]azalone-2-carboxamide | CHEMBL376135
TypeSmall organic molecule
Emp. Form.C23H33N5O4
Mol. Mass.443.5392
SMILESNC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1cnc([nH]1)C1CCCCC1)NC(=O)[C@H]1CCC(=O)C1
Structure
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n/a